Commentary on Genesis is the last work of Martin Luther, written during the last several years of his life. Luther's work follows the first volume of Psalms with critical and devotional remarks on the creation and on sin and the flood.

Martin Luther (1483-1546) was a German professor of theology, composer, priest, monk, and a seminal figure in the Protestant Reformation. Luther came to reject several teachings and practices of the Roman Catholic Church. He strongly disputed the Catholic view on indulgences and he proposed an academic discussion of the practice and efficacy of indulgences in his famous Ninety-five Theses of 1517. Luther's refusal to renounce all of his writings at the demand of Pope Leo X and the Holy Roman Emperor Charles V resulted in his excommunication by the Pope and condemnation as an outlaw by the Emperor.